Acids and Bases

Learning outcomes - after studying this topic, you should be able to:
  • explain the advantages of the Bronsted-Lowry acid-base definition over the Arrhenius definition
  • understand the relationships between pH, pOH, pKa, pKb and pKw
  • predict qualitatively the excess species in weak conjugate acid-base pairs at a given pH
  • calculate the pH, pOH, [H+] and [OH-] for aqueous solutions of strong acids and bases
  • predict qualitatively the relative acidities of strong acids
  • calculate the pH, pOH, [H+] and [OH-] for very diluite solutions of strong acids and bases
  • calculate the pH, pOH, [H+] and [OH-] for aqueous solutions of weak acids and bases
  • calculate the pKa of a weak, monoprotic acid from the pH of its solution
  • predict the sequence of strengths of acidities of weak, polyprotic acids
  • predict qualitatively the pH of salt solutions
  • calculate the pH of solutions of hydrated metal ions
  • identify Lewis acids and bases
  • explain the origin of buffering action
  • calculate the pH change for addition of acid or base to a buffer
  • choose an appropriate buffer for any pH value
  • explain how to prepare a buffer solution
  • explain the buffering action of HsCO3 / HCO3- in the blood
  • explain how to perform an acid-base titration
  • selection an indicator for the titration of any combination of acid and base
  • predict the charge of an amino acid and its direction of migration in electrophoresis given its pI
  • explain the origins of positive and negative charges on a protein
  • predict qualitatively the change in solubility of a protein with changing pH given its pI

Textbook and eBook References

Lecture Notes and Tutorial Worksheets & Answers

ChemCAL, iChem and Contributed Resources

Acids and Bases (Advanced) - Self Learning Questions (2)
Contributed by Adam Bridgeman
 
 
Acids and Bases (Advanced) - Self Learning Questions (1)
Contributed by Adam Bridgeman
 
 
Acids and Bases - Self Learning Questions (2)
Contributed by Adam Bridgeman
 
 
Acids and Bases - Self Learning Questions (1)
Contributed by Adam Bridgeman
 
 
Acid-Base Titrations
Contributed by Adam Bridgeman
 
 
Calculations with Weak Acids and Bases
Contributed by Adam Bridgeman
 
 
Weak Acids and Bases
Contributed by Adam Bridgeman
 
 
Acids and Bases
Contributed by Adam Bridgeman
 
 
pH of Strong Acids and Bases
Description: How to calculate the pH of a strong acids and strong bases
Tags: pH | strong acid | strong base
Contributed by Adam Bridgeman
 
 
Henderson-Hasselbalch problems
Tags: acid | base | buffer
Contributed by Adam Bridgeman
 
 
pH of strong acids and bases (short video tutorial)
Description: Revision tutorial on how to calculate the pH of strong acids and bases
Tags: pH | strong acids | strong bases
Contributed by Adam Bridgeman