Topics and learning outcomes

• Acids and Bases
  
  •  explain the advantages of the Bronsted-Lowry acid-base definition over the Arrhenius definition
  •  understand the relationships between pH, pOH, pK_a, pK_b and pK_w
  •  predict qualitatively the excess species in weak conjugate acid-base pairs at a given pH
  •  calculate the pH, pOH, [H⁺] and [OH^-] for aqueous solutions of strong acids and bases
  •  predict qualitatively the relative acidities of strong acids
  •  calculate the pH, pOH, [H⁺] and [OH^-] for very diluite solutions of strong acids and bases
  •  calculate the pH, pOH, [H⁺] and [OH^-] for aqueous solutions of weak acids and bases
  •  calculate the pK_a of a weak, monoprotic acid from the pH of its solution
  •  predict the sequence of strengths of acidities of weak, polyprotic acids
  •  predict qualitatively the pH of salt solutions
  •  calculate the pH of solutions of hydrated metal ions
  •  identify Lewis acids and bases
  •  explain the origin of buffering action
  •  calculate the pH change for addition of acid or base to a buffer
  •  choose an appropriate buffer for any pH value
  •  explain how to prepare a buffer solution
  •  explain the buffering action of H_sCO₃ / HCO₃^- in the blood
  •  explain how to perform an acid-base titration
  •  selection an indicator for the titration of any combination of acid and base
  •  predict the charge of an amino acid and its direction of migration in electrophoresis given its pI
  •  explain the origins of positive and negative charges on a protein
  •  predict qualitatively the change in solubility of a protein with changing pH given its pI

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Lecture notes, tutorial homework and resources

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Acids and Bases -